Psychedelics in the context of therapy are very different from our current medical paradigm.
These substances are not intended, at least in the research context right now, to be taken on a regular basis but instead to be taken on just a few occasions. So, there's a real flip as far as how we think about things in biological psychiatry versus how we think about psychedelic-assisted therapies.
Carhart-Harris, R. (2013). Psychedelic drugs, magical thinking, and psychosis. Journal of Neurology, Neurosurgery & Psychiatry, 84(e1).