Indications

As previously noted, psilocybin has been shown to be safe in a number of clinical trials, as well as effective in aiding with treatment for a range of mental health conditions (Halpern & Pope, 1999; Hasler et al., 2004; Studerus et al., 2011).

By 2005, for example, more than 2000 subjects had undergone psychedelic-assisted therapy in clinical trials with psilocybin (Metzner, 2005). Whether given alone or combined with therapy, psilocybin's ability to increase global integration in the brain leads to increased mental flexibility and interconnection, which is associated with antidepressant effects. This is also reflected in its demonstrated efficacy in reducing symptoms associated with the following conditions discussed on this page.

While the literature on psilocybin can be classified into either clinical research studies or observational research, this course focuses on clinical research studies.

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