Pooled phase-2 data showed that MDMA-assisted therapy for PTSD had an extremely high Cohen’s D effect size of 0.9, compared to that of two leading FDA-approved drug treatments for PTSD, roughly triple the effect size of the SSRI sertraline (0.31) and double that of the SSRI paroxetine (0.45) (Feduccia et al., 2019).
Pooled phase-2 data showed that MDMA-assisted therapy for PTSD had an extremely high Cohen’s D effect size of 0.9, compared to that of two leading FDA-approved drug treatments for PTSD, roughly triple the effect size of the SSRI sertraline (0.31) and double that of the SSRI paroxetine (0.45) (Feduccia et al., 2019).
Building on what we learned last module about depression and anxiety, our focus this module will be on post-traumatic stress. We will look at how post-traumatic stress disorder is diagnosed in the DSM, including a commonly used screening and monitoring tool. We will also discuss common comorbidities, of which anxiety and depression are included, as well as other transdiagnostic considerations.
Upon successful completion of the module, you will be able to:
Feduccia, A. A., Jerome, L., Yazar-Klosinski, B., Emerson, A., Mithoefer, M. C., & Doblin, R. (2019). Breakthrough for Trauma Treatment: Safety and Efficacy of MDMA-Assisted Psychotherapy Compared to Paroxetine and Sertraline. Frontiers in psychiatry, 10, 650.